SUBSTANCES AND METHODS PROHIBITED AT ALL TIMES

S1. ANABOLIC AGENTS
Anabolic agents are prohibited.
1. Anabolic Androgenic Steroids (AAS)
a. Exogenous* AAS, including:
1-androstendiol (5α-androst-1-ene-3β,17β-diol ); 1-androstendione (5α-
androst-1-ene-3,17-dione); bolandiol (19-norandrostenediol); bolasterone;
boldenone; boldione (androsta-1,4-diene-3,17-dione); calusterone;
clostebol; danazol (17α-ethynyl-17β-hydroxyandrost-4-eno[2,3-d]isoxazole);
dehydrochlormethyltestosterone (4-chloro-17β-hydroxy-17α-methylandrosta-
1,4-dien-3-one); desoxymethyltestosterone (17α-methyl-5α-androst-2-en-
17β-ol); drostanolone; ethylestrenol (19-nor-17α-pregn-4-en-17-ol);
fluoxymesterone; formebolone; furazabol (17β-hydroxy-17α-methyl-5α-
androstano[2,3-c]-furazan); gestrinone; 4-hydroxytestosterone (4,17β-
dihydroxyandrost-4-en-3-one); mestanolone; mesterolone; metenolone;
methandienone (17β-hydroxy-17α-methylandrosta-1,4-dien-3-one);
methandriol; methasterone (2α, 17α-dimethyl-5α-androstane-3-one-17β-ol);
methyldienolone (17β-hydroxy-17α-methylestra-4,9-dien-3-one); methyl-1-
testosterone (17β-hydroxy-17α-methyl-5α-androst-1-en-3-one);
methylnortestosterone (17β-hydroxy-17α-methylestr-4-en-3-one);
methyltrienolone (17β-hydroxy-17α-methylestra-4,9,11-trien-3-one);
methyltestosterone; mibolerone; nandrolone; 19-norandrostenedione
(estr-4-ene-3,17-dione); norboletone; norclostebol; norethandrolone;
oxabolone; oxandrolone; oxymesterone; oxymetholone; prostanozol
([3,2-c]pyrazole-5α-etioallocholane-17β-tetrahydropyranol); quinbolone;
stanozolol; stenbolone; 1-testosterone (17β-hydroxy-5α-androst-1-en-3-
one); tetrahydrogestrinone (18a-homo-pregna-4,9,11-trien-17β-ol-3-one);
trenbolone and other substances with a similar chemical structure or similar
biological effect(s).
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b. Endogenous** AAS:
S2. HORMONES AND RELATED SUBSTANCES
The following substances and their releasing factors, are prohibited:
1. Erythropoietin (EPO);
2. Growth Hormone (hGH), Insulin-like Growth Factors (e.g. IGF-1),
Mechano Growth Factors (MGFs);
3. Gonadotrophins (e.g. LH, hCG), prohibited in males only;
4. Insulins;
5. Corticotrophins.
and other substances with similar chemical structure or similar biological effect(s).
Unless the Athlete can demonstrate that the concentration was due to a
physiological or pathological condition, a Sample will be deemed to contain a
Prohibited Substance (as listed above) where the concentration of the Prohibited
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Substance or its metabolites and/or relevant ratios or markers in the Athlete’s
Sample so exceeds the range of values normally found in humans that it is
unlikely to be consistent with normal endogenous production.
If a laboratory reports, using a reliable analytical method, that the Prohibited
Substance is of exogenous origin, the Sample will be deemed to contain a
Prohibited Substance and shall be reported as an Adverse Analytical Finding.
S3. BETA-2 AGONISTS
All beta-2 agonists including their D- and L-isomers are prohibited.
As an exception, formoterol, salbutamol, salmeterol and terbutaline when
administered by inhalation, require an abbreviated Therapeutic Use Exemption.
Despite the granting of any form of Therapeutic Use Exemption, a concentration
of salbutamol (free plus glucuronide) greater than 1000 ng/mL will be considered
an Adverse Analytical Finding unless the Athlete proves that the abnormal result
was the consequence of the therapeutic use of inhaled salbutamol.
S4. HORMONE ANTAGONISTS AND MODULATORS
The following classes are prohibited:
1. Aromatase inhibitors including, but not limited to: anastrozole,
letrozole, aminoglutethimide, exemestane, formestane, testolactone.
2. Selective estrogen receptor modulators (SERMs) including, but not
limited to: raloxifene, tamoxifen, toremifene.
3. Other anti-estrogenic substances including, but not limited to:
clomiphene, cyclofenil, fulvestrant.
4. Agents modifying myostatin function(s) including but not limited to:
myostatin inhibitors.
S5. DIURETICS AND OTHER MASKING AGENTS
Masking agents are prohibited. They include:
Diuretics*, epitestosterone, probenecid, alpha-reductase inhibitors (e.g.
finasteride, dutasteride), plasma expanders (e.g. albumin, dextran,
hydroxyethyl starch) and other substances with similar biological effect(s).
Diuretics include:
Acetazolamide, amiloride, bumetanide, canrenone, chlorthalidone,
etacrynic acid, furosemide, indapamide, metolazone, spironolactone,
thiazides (e.g. bendroflumethiazide, chlorothiazide, hydrochlorothiazide),